SCHEMBL4120737

SCHEMBL4120737

C=CC(=O)NN1CN(NC(=O)C=C)CN(NC(=O)C=C)C1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TGM2 P21980 8/20 0.33
F13A1 P00488 3/20 0.33
TGM1 P22735 3/20 0.33
LMNA P02545 2/20 0.32
FGFR4 P22455 1/20 0.30
TGM3 Q08188 1/20 0.30
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL907519 0.84 TSHR (0.40) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL28988331 0.84
SCHEMBL26690315 0.80
SCHEMBL1337362 0.80 TGM2 (0.42) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL615220 0.78 HTT (0.41) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL27091885 0.78 TSHR (0.38) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL2733784 0.75 CA12 (0.53) MAPK1LMNA
SCHEMBL9420528 0.75 TSHR (0.33) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL3753325 0.75 TGM2 (0.45) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL27385459 0.75 TSHR (0.35) TSHRALDH1A1MAPK1TDP1TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777385-A Highly branched wood fiber reinforcing agent and preparation method and application thereof 浙江九本环保技术有限公司 2024-03-29 CN claimed
CN-116144049-A Biodegradable high-solid-content enhanced water filtering agent and preparation method and application thereof 九洲生物技术(苏州)有限公司 2023-05-23 CN claimed
CN-114293399-B Chemically modified papermaking filler and preparation method thereof 九洲生物技术(苏州)有限公司 2022-10-21 CN claimed
CN-114293399-A Chemically modified papermaking filler and preparation method thereof 九洲生物技术(苏州)有限公司 2022-04-08 CN claimed
US-20090250670-A1 PHOTOCHROMIC FILMS AND METHOD FOR MANUFACTURING THE SAME HYUNDAI MOTOR COMPANY (KR) 2009-10-08 US claimed
US-20260008951-A1 HYDROGEN SULFIDE SCAVENGING COMPOSITIONS SWELLFIX UK LIMITED (GB) 2026-01-08 US disclosed
EP-4555037-A1 HYDROGEN SULFIDE SCAVENGING COMPOSITIONS Swellfix UK Limited (GB) 2025-05-21 EP disclosed
CN-117777385-A Highly branched wood fiber reinforcing agent and preparation method and application thereof 浙江九本环保技术有限公司 2024-03-29 CN disclosed
WO-2024013492-A1 HYDROGEN SULFIDE SCAVENGING COMPOSITIONS SWELLFIX UK LIMITED (GB) 2024-01-18 WO disclosed
CN-116144049-A Biodegradable high-solid-content enhanced water filtering agent and preparation method and application thereof 九洲生物技术(苏州)有限公司 2023-05-23 CN disclosed
CN-114293399-B Chemically modified papermaking filler and preparation method thereof 九洲生物技术(苏州)有限公司 2022-10-21 CN disclosed
CN-114293399-A Chemically modified papermaking filler and preparation method thereof 九洲生物技术(苏州)有限公司 2022-04-08 CN disclosed
CN-103306136-B Crosslinker composition, antigen fibrillation solution spin cellulose fibre and their preparation methods CHINESE TEXTILE SCIENTIFIC RESEARCH INST. (CN) 2016-03-30 CN disclosed
US-20090250670-A1 PHOTOCHROMIC FILMS AND METHOD FOR MANUFACTURING THE SAME HYUNDAI MOTOR COMPANY (KR) 2009-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008951-A1 HYDROGEN SULFIDE SCAVENGING COMPOSITIONS TST, CBS, ABCB7 TSHR 4164/4885ALDH1A1 2278/4885MAPK1 1407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.