SCHEMBL273858

SCHEMBL273858

CCN(CC)CCNCc1cccc(C(=O)Nc2scc(C)c2C(=O)N/N=C/c2ccc(Cl)c(C(F)(F)F)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC34A2 O95436 11/20 0.55
ADCYAP1R1 P41586 5/20 0.35
LMNA P02545 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
BRAF P15056 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL267084 1.00 SLC34A2 (0.55) SLC34A2ADCYAP1R1LMNAGAAMAPT
SCHEMBL267083 1.00 SLC34A2 (0.55) SLC34A2ADCYAP1R1LMNAGAAMAPT
SCHEMBL266258 0.91 SLC34A2 (0.60) SLC34A2ADCYAP1R1
SCHEMBL266259 0.91 SLC34A2 (0.60) SLC34A2ADCYAP1R1
SCHEMBL274446 0.91 SLC34A2 (0.60) SLC34A2ADCYAP1R1
SCHEMBL265976 0.89 SLC34A2 (0.49) SLC34A2ADCYAP1R1LMNAGAAMAPT
SCHEMBL273921 0.89 SLC34A2 (0.65) SLC34A2ADCYAP1R1
SCHEMBL265977 0.89 SLC34A2 (0.49) SLC34A2ADCYAP1R1LMNAGAAMAPT
SCHEMBL265943 0.89 SLC34A2 (0.65) SLC34A2ADCYAP1R1
SCHEMBL273728 0.89 SLC34A2 (0.49) SLC34A2ADCYAP1R1LMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120115851-A1 COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120115851-A1 COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-05-10 US disclosed
US-8134015-B2 Compound inhibiting in vivo phosphorous transport and medicine containing the same KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-03-13 US disclosed
US-8134015-B2 Compound inhibiting in vivo phosphorous transport and medicine containing the same KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115851-A1 COMPOUND INHIBITING IN VIVO PHOSPHORUS TRANSPORT AND MEDICINE CONTAINING THE SAME SLC34A1, SLC34A2, SLC20A2 SLC34A2 2/4885ADCYAP1R1 1219/4885LMNA 1925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.