Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.72 |
| ▸ | PGR | P06401 | 5/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | USP2 | O75604 | 3/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | MLNR | O43193 | 1/20 | 0.72 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.72 |
| ▸ | PPARG | P37231 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582821 | 0.91 | NR3C1 (0.80) | NR3C1CYP3A4PGRLMNAUSP2 | |
| SCHEMBL11582817 | 0.91 | NR3C1 (0.80) | NR3C1CYP3A4PGRLMNAUSP2 | |
| SCHEMBL11849050 | 0.91 | NR3C1 (0.80) | NR3C1CYP3A4PGRLMNAUSP2 | |
| SCHEMBL32672362 | 0.90 | NR3C1 (0.69) | NR3C1CYP3A4PGRLMNAUSP2 | |
| SCHEMBL11580982 | 0.86 | NR3C1 (0.86) | NR3C1CYP3A4PGRLMNAUSP2 | |
| SCHEMBL564964 | 0.86 | NR3C1 (0.86) | NR3C1CYP3A4PGRLMNAUSP2 | |
| SCHEMBL11582111 | 0.86 | NR3C1 (0.86) | NR3C1CYP3A4PGRLMNAUSP2 | |
| SCHEMBL11037205 | 0.85 | NR3C1 (0.83) | NR3C1CYP3A4PGRLMNAUSP2 | |
| Betamethasone Benzoate SCHEMBL49469 | 0.85 | NR3C1 (0.77) | NR3C1CYP3A4PGRUSP2MMP1 | |
| Betamethasone Benzoate SCHEMBL11878006 | 0.85 | NR3C1 (0.77) | NR3C1CYP3A4PGRUSP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059237-A2 | NOVEL GLUCOCORTICOID RECEPTOR AGONISTS AND IMMUNOCONJUGATES THEREOF | ADCENTRX THERAPEUTICS INC. (US) | 2024-03-21 | — | — | WO | disclosed |