Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Betamethasone Benzoate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 known ✓ | P04150 | 18/20 | 0.77 |
| ▸ | PGR | P06401 | 4/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | MMP1 | P03956 | 17/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betamethasone Benzoate SCHEMBL11878006 | 1.00 | NR3C1 (0.77) | NR3C1PGRMEN1USP2CYP3A4 | |
| Betamethasone Benzoate SCHEMBL11877997 | 1.00 | NR3C1 (0.77) | NR3C1PGRMEN1USP2CYP3A4 | |
| Betamethasone Benzoate SCHEMBL2954925 | 1.00 | NR3C1 (0.77) | NR3C1PGRMEN1USP2CYP3A4 | |
| Betamethasone Benzoate SCHEMBL21682645 | 0.98 | NR3C1 (0.77) | NR3C1PGRMEN1USP2CYP3A4 | |
| Betamethasone Benzoate SCHEMBL6898101 | 0.94 | NR3C1 (0.88) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11585136 | 0.94 | NR3C1 (0.67) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11582817 | 0.93 | NR3C1 (0.80) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11582821 | 0.93 | NR3C1 (0.80) | NR3C1PGRMEN1USP2CYP3A4 | |
| SCHEMBL11849050 | 0.93 | NR3C1 (0.80) | NR3C1PGRMEN1USP2CYP3A4 | |
| Betamethasone Dipropionate SCHEMBL5489443 | 0.93 | NR3C1 (0.83) | NR3C1PGRMEN1USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3793 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139030-A1 | CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION | SHATTUCK LABS INC (US) | 2026-05-21 | — | — | US | claimed |
| WO-2025054169-A1 | COMPOSITIONS AND METHODS FOR TOPICAL TREATMENT | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2025-03-13 | — | — | WO | claimed |
| EP-4426725-A2 | CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION | Shattuck Labs, Inc. (US) | 2024-09-11 | — | — | EP | claimed |
| CN-118475599-A | Chimeric proteins for the treatment of skin inflammation | 沙塔克实验室有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118141762-B | Foam-type pharmaceutical agent and foam composition for topical application | 北京罗诺强施医药技术研发中心有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-118141762-A | Foam-type pharmaceutical agent and foam composition for topical application | 北京罗诺强施医药技术研发中心有限公司 | 2024-06-07 | — | — | CN | claimed |
| EP-3993715-B1 | IMPLANTATION NEEDLE FOR INSERTING A SUBCUTANEOUSLY INSERTABLE ELEMENT INTO A BODY TISSUE | HOFFMANN LA ROCHE (CH) | 2024-04-17 | — | — | EP | claimed |
| CN-117500823-A | Chimeric proteins in autoimmunity | 沙塔克实验室有限公司 | 2024-02-02 | — | — | CN | claimed |
| EP-4305051-A1 | CHIMERIC PROTEINS IN AUTOIMMUNITY | Shattuck Labs, Inc. (US) | 2024-01-17 | — | — | EP | claimed |
| CN-116507626-A | Compositions and methods for modulating short-chain dehydrogenase activity | 罗迪奥治疗公司 | 2023-07-28 | — | — | CN | claimed |
| US-4432964-A | Topical composition containing steroid in two forms released independently from polymeric carrier | ALZA CORPORATION (US) | 1984-02-21 | — | — | US | claimed |
| US-4376767-A | ANTIBIOTICS AND PHARMACEUTICALS | MERCK & CO., INC. (US) | 1983-03-15 | — | — | US | claimed |
| EP-0068553-A1 | Topical antimicrobial anti-inflammatory compositions | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | claimed |
| US-4346709-A | Drug delivery devices comprising erodible polymer and erosion rate modifier | ALZA CORPORATION (US) | 1982-08-31 | — | — | US | claimed |
| US-4343798-A | Topical antimicrobial anti-inflammatory compositions | THE PROCTER & GAMBLE COMPANY (US) | 1982-08-10 | — | — | US | claimed |
| EP-0055870-A1 | Pyridylmethyl esters of selected bio-affecting carboxylic acids, process for preparing and pharmaceutical composition comprising the same | MERCK & CO. INC. (US) | 1982-07-14 | — | — | EP | claimed |
| EP-0051278-A1 | Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-05-12 | — | — | EP | claimed |
| US-4294852-A | WATER, AN ALIPHATIC ALCOHOL AND AN ORGANIC ACID TO ADJUST THE PH OF THE VEHICLE | JOHNSON & JOHNSON (US) | 1981-10-13 | — | — | US | claimed |
| US-4279900-A | ANTIINFLAMMATORY | INTREX RESEARCH CORPORATION (US) | 1981-07-21 | — | — | US | claimed |
| US-4013792-A | BETAMETHASONE BENZOATE AND NEOMYCIN SULFATE IN ALCOHOLCELLULOSE-SODIUM CHLORIDE GEL | WARNER-LAMBERT COMPANY (US) | 1977-03-22 | — | — | US | claimed |