Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fadolmidine SCHEMBL7917217 | 0.80 | ESR1 (0.59) | CYP19A1HRH3HRH4HTR3A | |
| SCHEMBL7791634 | 0.80 | HTR3A (0.44) | HRH3HRH4HTR3ATAAR1 | |
| Fadolmidine SCHEMBL1649867 | 0.78 | ESR1 (0.57) | CYP19A1HRH3HRH4HTR3A | |
| SCHEMBL7800815 | 0.77 | HRH3 (0.44) | HRH3HRH4HTR3ATAAR1 | |
| SCHEMBL1340417 | 0.74 | HTR6 (0.48) | HTR6 | |
| SCHEMBL1339698 | 0.74 | HTR6 (0.48) | HTR6 | |
| SCHEMBL1339435 | 0.74 | HTR6 (0.48) | HTR6CYP19A1 | |
| SCHEMBL1338621 | 0.74 | HTR6 (0.48) | HTR6 | |
| SCHEMBL9311027 | 0.72 | HTR6 (0.75) | HTR6CYP19A1 | |
| SCHEMBL22606737 | 0.71 | HTR6 (0.55) | HTR6CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068592-C | Imidazole derivatives having affinity for alpha 2 receptors activity | ORION YHTYMAE OY (FI) | 2001-07-18 | — | — | CN | disclosed |
| CN-1198741-A | Imidazole derivatives having affinity for alpha 2 receptor activity | ORION YHTYMAE OY (FI) | 1998-11-11 | — | — | CN | disclosed |