Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70565 | 0.89 | AKR1B1 (0.71) | AKR1B1CYP1A2CYP2C19TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL8922940 | 0.87 | AKR1B1 (0.68) | AKR1B1CYP1A2CYP2C19TSHRKDM4E | |
| SCHEMBL4402323 | 0.83 | AKR1B1 (0.62) | AKR1B1CYP1A2CYP2C19TSHRKDM4E | |
| SCHEMBL29276301 | 0.82 | AKR1B1 (0.48) | AKR1B1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL27315443 | 0.82 | KDM4E (0.46) | KDM4EHPGDLMNAMAPTPOLB | |
| SCHEMBL15586044 | 0.82 | SLC7A5 (0.41) | CYP1A2CYP2C19POLBALDH1A1 | |
| SCHEMBL1401775 | 0.81 | AKR1B1 (0.60) | AKR1B1CYP1A2CYP2C19TSHRKDM4E | |
| SCHEMBL4557746 | 0.79 | AKR1B1 (0.64) | AKR1B1CYP1A2CYP2C19TSHRKDM4E | |
| SCHEMBL1515871 | 0.79 | AKR1B1 (0.58) | AKR1B1CYP1A2CYP2C19TSHRKDM4E | |
| SCHEMBL2353171 | 0.79 | FOLH1 (0.60) | AKR1B1CYP1A2CYP2C19TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332871-B | Cyclohexyl substituted benzothiazole derivative for inhibiting programmed cell necrosis and application thereof | 中国人民解放军海军军医大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-116332871-A | Cyclohexyl substituted benzothiazole derivative for inhibiting programmed cell necrosis and application thereof | 中国人民解放军海军军医大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-1093536-C | 5-lipoxygenase inhibitors | PFIZER (US) | 2002-10-30 | — | — | CN | disclosed |
| CN-1169722-A | 5-lipoxygenase inhibitors | PFIZER (US) | 1998-01-07 | — | — | CN | disclosed |