Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339219 | 0.89 | CA2 (0.54) | KDM4EPOLBLMNAMAPK1CA2 | |
| SCHEMBL31346922 | 0.82 | PRSS1 (0.50) | KDM4EPOLBLMNAMAPK1CA2 | |
| SCHEMBL21728869 | 0.82 | AKR1B1 (0.58) | KDM4EPOLBLMNACA2HPGD | |
| SCHEMBL27387406 | 0.82 | AKR1B1 (0.58) | KDM4EPOLBLMNACA2ALDH1A1 | |
| SCHEMBL7770968 | 0.82 | ENPP2 (0.52) | KDM4ECA2ALDH1A1NFKB1 | |
| SCHEMBL28031264 | 0.82 | PRSS1 (0.50) | KDM4EPOLBLMNAMAPK1CA2 | |
| SCHEMBL29351393 | 0.80 | CA2 (0.45) | KDM4EPOLBLMNAMAPK1CA2 | |
| SCHEMBL22265815 | 0.80 | CA2 (0.45) | KDM4EPOLBLMNAMAPK1CA2 | |
| SCHEMBL2029757 | 0.80 | MAPK8 (0.52) | — | |
| SCHEMBL7770956 | 0.80 | LMNA (0.46) | KDM4EPOLBLMNAMAPK1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053666-C | Benzoheterocyclic compounds | OTSUKA PHARMA CO LTD (JP) | 2000-06-21 | — | — | CN | disclosed |
| CN-1030237-A | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1989-01-11 | — | — | CN | disclosed |