Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 13/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2738803 | 0.83 | P2RX4 (0.58) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL2738800 | 0.83 | P2RX4 (0.51) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL220291 | 0.81 | P2RX4 (0.58) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL21473321 | 0.76 | P2RX4 (0.57) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL220840 | 0.75 | P2RX4 (0.59) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL220994 | 0.74 | P2RX4 (0.54) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL14714325 | 0.71 | P2RX4 (0.67) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL15603438 | 0.70 | P2RX4 (0.66) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11113845 | 0.69 | P2RX4 (0.67) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11721111 | 0.68 | P2RX4 (0.71) | P2RX4LMNATSHRMAPK1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |