Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 15/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2738800 | 0.89 | P2RX4 (0.51) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL220994 | 0.87 | P2RX4 (0.54) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL2738803 | 0.87 | P2RX4 (0.58) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL220291 | 0.81 | P2RX4 (0.58) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL21473321 | 0.76 | P2RX4 (0.57) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL2738802 | 0.75 | P2RX4 (0.52) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL9555484 | 0.75 | P2RX4 (1.00) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11113845 | 0.75 | P2RX4 (0.67) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL13051502 | 0.75 | BCHE (0.68) | P2RX4P2RX1P2RX3P2RX7MTNR1A | |
| SCHEMBL15603438 | 0.73 | P2RX4 (0.66) | P2RX4LMNATSHRMAPK1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-20060035863-A1 | Noncardiotoxic pharmaceutical compounds | B&G PARTNERS, LLC | 2006-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035863-A1 | Noncardiotoxic pharmaceutical compounds | KCNN3, TNNI3, TNNT2 | P2RX4 2185/4885LMNA 204/4885TSHR 1289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.