⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL15006613 | 0.96 | — | — | |
| SCHEMBL28194690 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL1338990 | 0.96 | — | — | |
| Bromide SCHEMBL15006549 | 0.96 | — | — | |
| Ethyne SCHEMBL9364953 | 0.93 | — | — | |
| SCHEMBL2055336 | 0.87 | — | — | |
| Oxalic Acid SCHEMBL29212837 | 0.83 | GABRP (0.37) | — | |
| Acetic Acid SCHEMBL29212835 | 0.81 | GABRP (0.35) | — | |
| SCHEMBL300703 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL15017471 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290338-A | Building block 6-azaspiro [2.5] octane synthesized by Sovilnesib as anticancer medicine for clinical research and its synthesizing process | 上海苏博医药科技有限公司 | 2024-07-05 | — | — | CN | claimed |
| US-12018010-B2 | Method for preparing efinaconazole using ionic liquid as medium | DAEBONG LS CO., LTD. (KR) | 2024-06-25 | — | — | US | claimed |
| CN-117820255-A | Application of catalyst and degradation method of ester substance | 上海科技大学 | 2024-04-05 | — | — | CN | claimed |
| EP-3915981-B1 | METHOD FOR PREPARATION OF EFINACONAZOLE IN IONIC LIQUID MEDIUM | DAEBONG LS CO LTD (KR) | 2024-04-03 | — | — | EP | claimed |
| CN-113330006-B | Novel preparation method of efroconazole by taking ionic liquid as medium | 大峰LS株式会社 | 2023-11-07 | — | — | CN | claimed |
| CN-116589447-A | Chemical-enzymatic process synthesis method of efroconazole | 浙江工业大学 | 2023-08-15 | — | — | CN | claimed |
| CN-115327000-B | Method for detecting 4-methylenepiperidine in efinaconazole | 深圳市海滨制药有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-115327000-A | Method for detecting 4-methylenepiperidine in efinaconazole | 深圳市海滨制药有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-110770220-B | Preparation and purification method of efinaconazole | 科研制药株式会社 | 2022-08-12 | — | — | CN | claimed |
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2007-02-08 | — | — | US | claimed |
| WO-2006113140-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | ELAN PHARMACEUTICALS, INC. (US) | 2006-10-26 | — | — | WO | claimed |
| EP-1080076-B1 | IMPROVED METHOD FOR PREPARING PHARMACEUTICALLY VALUABLE NORBENZOMORPHANE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | claimed |
| CN-1125814-C | Process for preparation of 4-methylenepiperidines | KAKEN PHARMA CO LTD (JP) | 2003-10-29 | — | — | CN | claimed |
| EP-0881215-B1 | PROCESS FOR THE PREPARATION OF 4-METHYLENEPIPERIDINES | KAKEN PHARMA CO LTD (JP) | 2001-09-05 | — | — | EP | claimed |
| US-6124459-A | Process for preparing pharmaceutically useful norbenzomorphane derivative | BOEHRINGER INGELHEIM KG (DE) | 2000-09-26 | — | — | US | claimed |
| US-6054586-A | Process for the preparation of 4-methylenepiperidine | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | claimed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | claimed |
| EP-0881215-A1 | PROCESS FOR THE PREPARATION OF 4-METHYLENEPIPERIDINES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | claimed |
| CN-1198156-A | Process for preparation of 4-methylenepiperidines | KAKEN PHARMA CO LTD (JP) | 1998-11-04 | — | — | CN | claimed |