⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15017471 | 0.97 | — | — | |
| SCHEMBL7710653 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL8820148 | 0.79 | — | — | |
| SCHEMBL273897 | 0.79 | — | — | |
| Trifluoroacetic Acid SCHEMBL22655475 | 0.78 | KDM1A (0.36) | — | |
| Hydrochloric Acid SCHEMBL1338990 | 0.76 | — | — | |
| Bromide SCHEMBL15006549 | 0.76 | — | — | |
| Iodide SCHEMBL15006613 | 0.76 | — | — | |
| SCHEMBL28194690 | 0.76 | — | — | |
| Ethyne SCHEMBL9364953 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262290-B | 4-methylene pyrrolidine-2-thioketone compound, and synthetic method and application thereof | 华东师范大学 | 2024-03-22 | — | — | CN | claimed |
| CN-114262290-A | 4-methylene pyrrolidine-2-thioketone compound and synthesis method and application thereof | 华东师范大学 | 2022-04-01 | — | — | CN | claimed |
| CN-101869563-B | Peptide deformylase inhibitor containing 4-methylene pyrrolidine | UNIV EAST CHINA NORMAL | 2011-11-16 | — | — | CN | claimed |
| CN-101869563-A | Peptide deformylase inhibitor containing 4-methylene pyrrolidine | UNIV EAST CHINA NORMAL | 2010-10-27 | — | — | CN | claimed |
| US-12139497-B2 | Aryl, heteroaryl, and heterocyclic compounds for treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2024-11-12 | — | — | US | disclosed |
| WO-2024144149-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2024-07-04 | — | — | WO | disclosed |
| CN-114262290-B | 4-methylene pyrrolidine-2-thioketone compound, and synthetic method and application thereof | 华东师范大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-114262290-B | 4-methylene pyrrolidine-2-thioketone compound, and synthetic method and application thereof | 华东师范大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-114262290-B | 4-methylene pyrrolidine-2-thioketone compound, and synthetic method and application thereof | 华东师范大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-111417635-B | Pyrazolopyrimidines with anti-Respiratory Syncytial Virus (RSV) activity | 爱尔兰詹森科学公司 | 2024-01-02 | — | — | CN | disclosed |
| US-20230355622-A1 | METHODS OF CHEMOVACCINATION AGAINST PLASMODIUM INFECTIONS | MERCK SHARP & DOHME LLC (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230313169-A1 | PVA MEMBRANE IMMOBILIZED ENZYME AND PREPARATION METHOD THEREFOR | ASYMCHEM LIFE SCIENCE (TIANJIN) CO., LTD. (CN) | 2023-10-05 | — | — | US | disclosed |
| US-20070066630-A1 | Nitrogen-containing heterocyclic compounds and methods of use thereof | MERCK SHARP & DOHME LLC | 2007-03-22 | — | — | US | disclosed |
| US-20070043028-A1 | Compositions of novel opioid compounds and method of use thereof | DMK PHARMACEUTICALS CORPORATION | 2007-02-22 | — | — | US | disclosed |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION | 2007-02-22 | — | — | US | disclosed |
| US-20060106023-A1 | Novel imidazopyrazines as cyclin dependent kinase inhibitors | SCHERING CORPORATION | 2006-05-18 | — | — | US | disclosed |
| WO-2004043369-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043366-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| CN-1037149-A | The preparation method of 3-alkenyl-1-azabicyclo [3,2,0] hept-2-ene\"-2-carboxylic acid cpd | FUJISAWA PHARMACEUTICAL CO (JP) | 1989-11-15 | — | — | CN | disclosed |