Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 9/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.39 |
| ▸ | TSHR | P16473 | 9/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27397571 | 0.90 | USP2 (0.39) | USP2HPGDCYP2D6CYP3A4TSHR | |
| SCHEMBL27397562 | 0.88 | SLC6A2 (0.40) | USP2HPGDCYP2D6CYP3A4TSHR | |
| SCHEMBL7180636 | 0.85 | TACR2 (0.43) | KMT2ATACR2 | |
| SCHEMBL7174179 | 0.85 | TACR2 (0.43) | KMT2ATACR2 | |
| Hydrochloric Acid SCHEMBL4802792 | 0.84 | TACR2 (0.42) | KMT2ATACR2 | |
| Hydrochloric Acid SCHEMBL4800620 | 0.84 | TACR2 (0.42) | KMT2ATACR2 | |
| SCHEMBL27408143 | 0.84 | DRD4 (0.41) | USP2CYP2D6CYP3A4TSHRCYP1A2 | |
| SCHEMBL27408144 | 0.83 | TACR1 (0.42) | CYP2D6CYP3A4TSHRCYP1A2ALDH1A1 | |
| SCHEMBL4631280 | 0.80 | TACR2 (0.49) | USP2HPGDCYP2D6CYP3A4TSHR | |
| SCHEMBL7750393 | 0.80 | ADRB2 (0.39) | USP2HPGDCYP2D6CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089764-C | Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHESIZING LAB (FR) | 2002-08-28 | — | — | CN | disclosed |