Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174179 | 1.00 | TACR2 (0.43) | TACR2RORCKDM4EKMT2AMGLL | |
| Hydrochloric Acid SCHEMBL4802792 | 0.99 | TACR2 (0.42) | TACR2RORCKDM4EKMT2AMGLL | |
| Hydrochloric Acid SCHEMBL4800620 | 0.99 | TACR2 (0.42) | TACR2RORCKDM4EKMT2AMGLL | |
| SCHEMBL27418051 | 0.85 | SIGMAR1 (0.48) | TACR2KDM4EKMT2ASIGMAR1CCR3 | |
| SCHEMBL27392003 | 0.85 | USP2 (0.40) | TACR2KMT2A | |
| SCHEMBL27390996 | 0.83 | TACR2 (0.45) | TACR2RORCMGLLSIGMAR1POLB | |
| SCHEMBL27415048 | 0.80 | SIGMAR1 (0.44) | SIGMAR1DRD4OPRL1 | |
| SCHEMBL27390993 | 0.79 | SIGMAR1 (0.46) | TACR2KDM4EKMT2ASIGMAR1OPRL1 | |
| SCHEMBL4800783 | 0.79 | MEN1 (0.47) | TACR2RORCKMT2A | |
| SCHEMBL4630131 | 0.78 | HSD11B1 (0.36) | TACR2RORCSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200417-B1 | METHOD FOR PREPARING 2-(2-ARYLMORPHOLIN-2-YL)ETHANOL DERIVATIVES AND INTERMEDIATES | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| EP-1200417-A1 | METHOD FOR PREPARING 2-(2-ARYLMORPHOLIN-2-YL)ETHANOL DERIVATIVES AND INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001004105-A1 | METHOD FOR PREPARING 2-(2-ARYLMORPHOLIN-2-YL)ETHANOL DERIVATIVES AND INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2001-01-18 | — | — | WO | disclosed |