Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | AGER | Q15109 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161861 | 0.85 | APP (0.55) | APPAGERMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL10499088 | 0.85 | PRSS1 (0.50) | APPAGERMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL10499251 | 0.83 | PRSS1 (0.52) | APPAGERMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL10499489 | 0.83 | PRSS1 (0.52) | APPAGERMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL10499969 | 0.83 | PRSS1 (0.52) | APPAGERMAPTL3MBTL1ALDH1A1 | |
| Bromide SCHEMBL10499280 | 0.81 | PRSS1 (0.50) | APPAGERMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL30314739 | 0.78 | AGER (0.45) | AGERMAPTL3MBTL1ALDH1A1GAA | |
| SCHEMBL271536 | 0.78 | APP (0.50) | APPAGERMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL16245938 | 0.76 | APP (0.48) | APPAGERMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1955932 | 0.76 | MAPT (0.53) | APPAGERMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1091432-A | Can suppress the active peptide of hiv protease, its preparation with and medical use | SANKYO CO (JP) | 1994-08-31 | — | — | CN | disclosed |