Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.52 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499251 | 1.00 | PRSS1 (0.52) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL10499969 | 1.00 | PRSS1 (0.52) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Bromide SCHEMBL10499280 | 0.98 | PRSS1 (0.50) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL10499088 | 0.98 | PRSS1 (0.50) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL27394685 | 0.83 | APP (0.48) | APPAGERALDH1A1MAPTL3MBTL1 | |
| SCHEMBL14972359 | 0.82 | ALDH1A1 (0.55) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL1573489 | 0.80 | ESR1 (0.52) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL1953355 | 0.80 | ESR1 (0.52) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL10485907 | 0.80 | ESR1 (0.52) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL1954253 | 0.80 | ESR1 (0.52) | PRSS1F2PRSS2PRSS3TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |