Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18390549 | 0.86 | POLB (0.54) | PROKR1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL17714090 | 0.85 | PROKR1 (0.48) | PROKR1RAB9ASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL2386331 | 0.84 | PROKR1 (0.57) | PROKR1RAB9ASMN1; SMN2CCNCCDK8 | |
| SCHEMBL12108484 | 0.84 | PROKR1 (0.57) | PROKR1RAB9ASMN1; SMN2CCNCCDK8 | |
| SCHEMBL27153827 | 0.81 | AKR1C1 (0.49) | PROKR1RAB9ASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL18705015 | 0.81 | HRH3 (0.56) | PROKR1RAB9ASMN1; SMN2 | |
| SCHEMBL29051582 | 0.80 | SMN1; SMN2 (0.50) | PROKR1RAB9ASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL17714082 | 0.80 | SIGMAR1 (0.53) | PROKR1RAB9ASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL9104445 | 0.80 | SMN1; SMN2 (0.53) | PROKR1RAB9ASMN1; SMN2CCNCCDK8 | |
| SCHEMBL25848891 | 0.79 | ACHE (0.57) | PROKR1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3958867-B1 | SMALL MOLECULE BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE LLC (US) | 2024-06-26 | — | — | EP | disclosed |