Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23720774 | 0.71 | — | — | |
| SCHEMBL3514711 | 0.67 | — | — | |
| SCHEMBL8487410 | 0.63 | L3MBTL1 (0.41) | MAOAMAOBL3MBTL1CYP2C19CHRM2 | |
| SCHEMBL8499451 | 0.60 | L3MBTL1 (0.53) | MAOAMAOBL3MBTL1CYP2C19CHRM2 | |
| SCHEMBL12993113 | 0.60 | MAOA (0.34) | MAOAMAOBL3MBTL1CYP2C19CHRM2 | |
| SCHEMBL21537911 | 0.58 | MAOA (0.33) | MAOAMAOBL3MBTL1CYP2C19CHRM2 | |
| SCHEMBL12806639 | 0.58 | MAOA (0.33) | MAOAMAOBL3MBTL1CYP2C19 | |
| SCHEMBL26639396 | 0.58 | MAOA (0.33) | MAOAMAOBCYP2C19 | |
| SCHEMBL29313846 | 0.57 | MAOA (0.35) | MAOAMAOBCYP2C19CHRM2HTR1A | |
| SCHEMBL2071122 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3958867-B1 | SMALL MOLECULE BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE LLC (US) | 2024-06-26 | — | — | EP | disclosed |