Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661240 | 0.80 | PAM (0.52) | NPC1RAB9AGLATDP1HAO1 | |
| SCHEMBL6661243 | 0.80 | PAM (0.52) | NPC1RAB9AGLATDP1HAO1 | |
| SCHEMBL10458424 | 0.79 | SMN1; SMN2 (0.55) | NPC1RAB9AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27502891 | 0.78 | NPC1 (0.46) | NPC1RAB9AGLATDP1HAO1 | |
| SCHEMBL17486793 | 0.78 | KMT2A (0.59) | NPC1RAB9AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27835867 | 0.77 | HTT (0.49) | NPC1RAB9AGLATDP1HAO1 | |
| Hydrochloric Acid SCHEMBL27503547 | 0.77 | NPC1 (0.45) | NPC1RAB9AGLATDP1HAO1 | |
| SCHEMBL19398199 | 0.75 | NPC1 (0.59) | NPC1RAB9AL3MBTL1GLATDP1 | |
| SCHEMBL11689773 | 0.75 | HAO1 (0.64) | NPC1RAB9AL3MBTL1GLATDP1 | |
| SCHEMBL1507314 | 0.74 | MAOB (0.44) | NPC1RAB9AL3MBTL1GLATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1090278-A | Blood vessel tension peptide protoenzyme inhibitor-N-(2-amino-2-oxygen ethyl) succinic diamide derivative | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1994-08-03 | — | — | CN | disclosed |