SCHEMBL1507314

SCHEMBL1507314

CCNC=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.44
RELA Q04206 2/20 0.44
NPC1 O15118 3/20 0.42
RAB9A P51151 2/20 0.42
CHAT P28329 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HTR2A P28223 3/20 0.39
TRPA1 O75762 1/20 0.39
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10628442 0.83 HDAC3 (0.42) MAOBRELANPC1RAB9ACHAT
SCHEMBL12903021 0.80 NFE2L2 (0.45) RELANPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL10628647 0.79 HDAC3 (0.51) MAOBRELANPC1RAB9ATDP1
SCHEMBL1506756 0.78 EGFR (0.54) TDP1ALDH1A1SMN1; SMN2
SCHEMBL11281860 0.77 MAOB (0.44) MAOBNPC1RAB9ATRPA1ALDH1A1
SCHEMBL10628483 0.77 EGFR (0.56) TDP1ALDH1A1SMN1; SMN2
SCHEMBL27702754 0.77 CHAT (0.41) MAOBRELANPC1RAB9ACHAT
SCHEMBL10623848 0.77 EGFR (0.56) TDP1ALDH1A1SMN1; SMN2
SCHEMBL27636014 0.77 EGFR (0.56) TDP1ALDH1A1SMN1; SMN2
SCHEMBL12903026 0.77 RELA (0.53) RELAL3MBTL1GLAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104870482-B Molecularly imprinted polymer and its purposes as anti-dandruff agent 莱雅公司 2017-10-24 CN disclosed
US-9486497-B2 Treatment of immunocompromised conditions THE UNIVERSITY OF QUEENSLAND (AU) 2016-11-08 US disclosed
US-20160193294-A1 COMPOSITIONS COMPRISING E-SELECTIN ANTAGONISTS AND USES THEREFOR THE UNIVERSITY OF QUEENSLAND (AU) 2016-07-07 US disclosed
EP-2333887-B1 METHOD FOR PRODUCING ANION EXCHANGE MEMBRANE FOR SOLID POLYMER ELECTROLYTE-TYPE FUEL CELL TOKUYAMA CORP (JP) 2016-06-01 EP disclosed
US-9254322-B2 Compositions comprising E-selectin antagonists and uses therefor THE UNIVERSITY OF QUEENSLAND (AU) 2016-02-09 US disclosed
CN-104880908-A Photosensitive resin composition SUMITOMO CHEMICAL CO 2015-09-02 CN disclosed
US-8399154-B2 Method for producing an anion-exchange membrane for a solid polymer electrolyte type fuel cell TOKUYAMA CORPORATION (JP) 2013-03-19 US disclosed
US-20110207028-A1 Method for Producing an Anion-Exchange Membrane for a Solid Polymer Electrolyte Type Fuel Cell TOKUYAMA CORPORATION (JP) 2011-08-25 US disclosed
EP-2333887-A1 METHOD FOR PRODUCING ANION EXCHANGE MEMBRANE FOR SOLID POLYMER ELECTROLYTE-TYPE FUEL CELL Tokuyama Corporation (JP) 2011-06-15 EP disclosed
US-20110104590-A1 Method for Producing Ion Conductivity Providing Agent for Catalyst Electrode Layer in Anion-Exchange Membrane Type Fuel Cell TOKUYAMA CORPORATION (JP) 2011-05-05 US disclosed
US-20110020270-A1 TREATMENT AND PROPHYLAXIS MATER MEDICAL RESEARCH INSTITUTE 2011-01-27 US disclosed
US-20110002881-A1 TREATMENT AND PROPHYLAXIS MATER MEDICAL RESEARCH INSTITUTE (AU) 2011-01-06 US disclosed
EP-1119660-A1 CELLULOSIC SUPPORT TREATMENT MORGAN ADHESIVES COMPANY (US) 2001-08-01 EP disclosed
WO-2001004418-A1 CELLULOSIC SUPPORT TREATMENT MORGAN ADHESIVES COMPANY (US) 2001-01-18 WO disclosed
US-5506275-A RESISTANCE TO ABRASION AND CRACKING ON FLEX BASF CORPORATION (US) 1996-04-09 US disclosed
US-5180799-A Organolithium-Organoaluminum Catalyst IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-01-19 US disclosed
EP-0434316-A1 Processes ZENECA LIMITED (GB) 1991-06-26 EP disclosed
US-4734351-A DISPERSION OF POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1988-03-29 US disclosed
CN-86103603-A The preparation method of the derivative of benzothiazine dioxide 1987-01-21 CN disclosed
EP-0091039-B1 ANTI-FOULING AGENT Nitto Kasei Co., Ltd. (JP) 1986-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110020270-A1 TREATMENT AND PROPHYLAXIS SELP, SELE, SELL MAOB 3229/4885RELA 2329/4885NPC1 2512/4885
US-20110002881-A1 TREATMENT AND PROPHYLAXIS SELP, SELE, SELPLG MAOB 2493/4885RELA 1978/4885NPC1 2248/4885
US-20160193294-A1 COMPOSITIONS COMPRISING E-SELECTIN ANTAGONISTS AND USES THEREFOR SELL, SELP, SELE MAOB 3994/4885RELA 2888/4885NPC1 2313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.