SCHEMBL27415348

SCHEMBL27415348

CC(C)(C)OC(=O)N1CCN(c2ccc3cnn(C4CCC(=O)NC4O)c(=O)c3c2)CC1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 5/20 0.44
CRBN Q96SW2 5/20 0.44
CDK4 P11802 1/20 0.41
CCND1 P24385 1/20 0.41
CCND2 P30279 1/20 0.41
CCND3 P30281 1/20 0.41
ALK Q9UM73 3/20 0.40
MAPT P10636 4/20 0.39
PDK2 Q15119 1/20 0.39
MEN1 O00255 1/20 0.39
TSHR P16473 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GPR119 Q8TDV5 4/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30905908 0.84 DDB1 (0.53) DDB1CRBNCDK4CCND1CCND2
SCHEMBL25141804 0.84 DDB1 (0.53) DDB1CRBNCDK4CCND1CCND2
SCHEMBL25141828 0.83 DDB1 (0.42) DDB1CRBNALKMAPTPDK2
SCHEMBL27397706 0.79 DDB1 (0.44) DDB1CRBNCDK4CCND1CCND2
SCHEMBL21477235 0.77 SUV39H2 (0.44) DDB1CRBNMAPTPDK2GPR119
SCHEMBL25141584 0.77 DDB1 (0.53) DDB1CRBNCDK4CCND1CCND2
SCHEMBL26250785 0.75 MTNR1A (0.37) SMN1; SMN2ALDH1A1
SCHEMBL26495773 0.75 DDB1 (0.46) DDB1CRBNMAPTPDK2GPR119
SCHEMBL24861147 0.74 DDB1 (0.33) DDB1CRBN
SCHEMBL22006011 0.73 PDK2 (0.49) DDB1CRBNMAPTPDK2GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024112119-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 WO disclosed