Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.36 |
| ▸ | FPR2 | P25090 | 6/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25093406 | 0.81 | PTPN1 (0.40) | SCN9APTPN1CNR2 | |
| SCHEMBL24959363 | 0.78 | APP (0.43) | KMT2ASCN9AFPR2PIM1NNMT | |
| SCHEMBL12569462 | 0.76 | PIM1 (0.39) | KMT2ASCN9AFPR2PIM1NNMT | |
| SCHEMBL10138886 | 0.74 | BACE1 (0.37) | KMT2APDE3BPDE3A | |
| SCHEMBL22768560 | 0.72 | NNMT (0.46) | PIM1NNMT | |
| SCHEMBL23717810 | 0.72 | CYP3A4 (0.37) | LMNACYP2C19PDE3BPDE3A | |
| SCHEMBL12871319 | 0.72 | NOTUM (0.34) | LMNACYP2C19PDE3BPDE3A | |
| SCHEMBL26137557 | 0.72 | CYP3A4 (0.37) | CYP2C19PDE3BPDE3A | |
| SCHEMBL11347729 | 0.71 | KMT2A (0.39) | KMT2ASCN9APIM1PTPN1NNMT | |
| SCHEMBL23886428 | 0.71 | KMT2A (0.42) | KMT2ASCN9AFPR2PIM1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050370-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | 1CBIO, INC. (US) | 2024-03-07 | — | — | WO | disclosed |