Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27398659 | 0.86 | FLT3 (0.36) | FLT3TGFBR1TP53GAAMAPT | |
| SCHEMBL27399925 | 0.82 | PIK3CA (0.40) | GRM2TGFBR1MAPT | |
| SCHEMBL31051300 | 0.79 | FLT3 (0.36) | FLT3TGFBR1TP53GAAMAPT | |
| SCHEMBL31051270 | 0.76 | GRM5 (0.37) | FLT3 | |
| SCHEMBL27398648 | 0.75 | TGFBR1 (0.43) | ADORA2AADORA1ADORA2BGRM2TGFBR1 | |
| SCHEMBL31051191 | 0.75 | TGFBR1 (0.39) | FLT3TGFBR1 | |
| SCHEMBL14041215 | 0.74 | TGFBR1 (0.43) | FLT3ADORA2AADORA1ADORA2BTGFBR1 | |
| SCHEMBL11306787 | 0.72 | LMNA (0.43) | TP53GAAMAPTMEN1KMT2A | |
| SCHEMBL11283541 | 0.72 | LMNA (0.43) | TP53GAAMAPTMEN1KMT2A | |
| SCHEMBL31051278 | 0.72 | FLT3 (0.36) | FLT3ADORA2AADORA1ADORA2BTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126404-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-20 | — | — | WO | disclosed |