Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 10/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399173 | 0.85 | TGFBR1 (0.41) | TGFBR1 | |
| SCHEMBL31051181 | 0.85 | TGFBR1 (0.41) | TGFBR1 | |
| SCHEMBL29907557 | 0.80 | TGFBR1 (0.46) | TGFBR1ADORA2AADORA1ADORA2B | |
| SCHEMBL27399217 | 0.80 | ADORA2A (0.47) | TGFBR1ADORA2AADORA1ADORA2B | |
| SCHEMBL27399151 | 0.75 | TGFBR1 (0.51) | TGFBR1CYP1A2 | |
| SCHEMBL31051236 | 0.74 | TGFBR1 (0.46) | TGFBR1ALDH1A1CYP1A2CYP3A4CLK4 | |
| SCHEMBL14041215 | 0.74 | TGFBR1 (0.43) | TGFBR1ADORA2AADORA1ADORA2BALDH1A1 | |
| SCHEMBL31452825 | 0.71 | ADORA1 (0.58) | ADORA2AADORA1CYP17A1USP2ALDH1A1 | |
| SCHEMBL7210230 | 0.71 | MAPK9 (0.59) | CYP17A1ALDH1A1 | |
| SCHEMBL22290188 | 0.70 | CYP17A1 (0.58) | CYP17A1USP2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126404-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-20 | — | — | WO | disclosed |