Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21671875 | 0.74 | SLC6A2 (0.41) | MEN1KMT2AMAPTPOLBCYP19A1 | |
| Dinitrophenylene SCHEMBL27494788 | 0.73 | TSHR (0.65) | TSHRTP53MEN1KMT2AMAPT | |
| SCHEMBL2491291 | 0.72 | MAPT (0.46) | KMT2AMAPTALDH1A1 | |
| SCHEMBL29992471 | 0.71 | MEN1 (0.49) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3481288 | 0.71 | MEN1 (0.49) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2846719 | 0.69 | CYP19A1 (0.48) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27718260 | 0.69 | PKM (0.44) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| Nitrobenzene SCHEMBL27471209 | 0.69 | TSHR (0.67) | TSHRTP53MEN1KMT2AMAPT | |
| SCHEMBL31036030 | 0.68 | SLC6A2 (0.48) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3193529 | 0.68 | ITGA4 (0.43) | TP53HTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1073175-A | Heterogeneous ring compound | WELLCOME FOUND (GB) | 1993-06-16 | — | — | CN | disclosed |