⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097865 | 0.93 | — | — | |
| SCHEMBL2382694 | 0.91 | CA2 (0.40) | — | |
| Urea SCHEMBL2682647 | 0.89 | CA2 (0.39) | — | |
| SCHEMBL829063 | 0.79 | — | — | |
| SCHEMBL27399684 | 0.79 | CA2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL10986584 | 0.77 | — | — | |
| SCHEMBL27508934 | 0.77 | — | — | |
| SCHEMBL4068512 | 0.75 | — | — | |
| SCHEMBL16611544 | 0.75 | — | — | |
| SCHEMBL17507593 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012817-A1 | THERAPEUTIC COMBINATIONS USEFUL IN THE TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE | WARNER-LAMBERT COMPANY (US) | 1993-07-08 | — | — | WO | claimed |
| WO-1993003717-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| US-5153191-A | Administering lorglumide or loxiglumide or salts thereof | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | claimed |
| US-20240217978-A1 | COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-07-04 | — | — | US | disclosed |
| EP-4326724-A1 | COMPOUND AS ADENOSINE A2A RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022224180-A1 | COMPOUND AS ADENOSINE A2A RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2022-10-27 | — | — | WO | disclosed |
| US-8735398-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-27 | — | — | US | disclosed |
| EP-2684039-A2 | PEPTIDE DEFORMYLASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-01-15 | — | — | EP | disclosed |
| US-20130085147-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | US | disclosed |
| US-8362020-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| WO-2012122450-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-09-13 | — | — | WO | disclosed |
| US-6492531-B1 | THE INVENTION CONCERNS CHOLECYSTOKININ (CCK) ANTAGONISTS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS. ESPECIALLY USEFUL ARE CCK.SUB.B ANTAGONISTS SUCH AS CI-988. | WARNER-LAMBERT COMPANY | 2002-12-10 | — | — | US | disclosed |
| EP-0686698-B1 | Biotechnological process for the production of cyclic S-alpha-aminocarboxylic acids and R-alpha-aminocarboxylic acid amides | LONZA AG (CH) | 2001-03-14 | — | — | EP | disclosed |
| US-5798311-A | INSECTICIDES | ROHM AND HAAS COMPANY (US) | 1998-08-25 | — | — | US | disclosed |
| US-5766893-A | ENZYME CULTURE | LONZA AG (CH) | 1998-06-16 | — | — | US | disclosed |
| US-5622846-A | RACEMIC MIXTURES OR OPTICALLY ACTIVE ISOMERS; MICROORGANISM WHICH USE THESE COMPOUNDS | LONZA AG (CH) | 1997-04-22 | — | — | US | disclosed |
| EP-0686698-A2 | Biotechnological process for the production of cyclic S-alpha-aminocarboxylic acids and R-alpha-aminocarboxylic acid amides | LONZA AG (CH) | 1995-12-13 | — | — | EP | disclosed |
| WO-1993003717-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5153191-A | Administering lorglumide or loxiglumide or salts thereof | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| US-4211876-A | PROSTAGLANDIN ANTAGONIST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-08 | — | — | US | disclosed |