SCHEMBL27400

SCHEMBL27400

CCC([O])c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
POLB P06746 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MIF P14174 1/20 0.42
HSD17B10 Q99714 1/20 0.41
TAAR1 Q96RJ0 3/20 0.41
HTR2A P28223 2/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
HRH1 P35367 1/20 0.41
HKDC1 Q2TB90 1/20 0.41
TRPA1 O75762 1/20 0.41
AOC3 Q16853 1/20 0.39
NOS3 P29474 1/20 0.39
NOS2 P35228 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CCR5 P51681 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL432757 0.80 AOC3 (0.46) LMNAPOLBTAAR1HTR2ACES2
SCHEMBL83018 0.79 LMNA (0.52) LMNAPOLBMEN1KMT2AMIF
SCHEMBL30034760 0.79 LMNA (0.52) LMNAPOLBMEN1KMT2AMIF
SCHEMBL4278718 0.78 CES2 (0.44) LMNATAAR1HTR2ACES2CES1
SCHEMBL10610871 0.77 CYP1A2 (0.43) HSD17B10HTR2A
Hydrochloric Acid SCHEMBL28970405 0.77 LMNA (0.50) LMNAMIFTAAR1HTR2ACES2
SCHEMBL5006192 0.77 LMNA (0.50) LMNAPOLBMEN1KMT2AMIF
SCHEMBL921888 0.77 POLB (0.49) LMNAPOLBHTR2AHRH1
SCHEMBL17534839 0.77 POLB (0.49) LMNAPOLBHTR2AHRH1
SCHEMBL4282489 0.76 CES2 (0.42) LMNATAAR1HTR2ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2467 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043636-B2 Method for producing triarylorganoborates COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-07-23 US claimed
CN-118184972-A CO with side chain containing two double bond functional groups2Base polyester and preparation method thereof 青岛科技大学 2024-06-14 CN claimed
CN-114409880-B Preparation method of recyclable bio-based polyester 青岛科技大学 2023-09-01 CN claimed
CN-116375993-A Simple method for preparing high molecular weight modifiable copolyester 青岛科技大学 2023-07-04 CN claimed
CN-114989725-B Corrosion-resistant water-based silicon modified polyester can-making paint and preparation method thereof 深圳市深赛尔股份有限公司 2023-06-02 CN claimed
CN-114276524-B Preparation method of high molecular weight degradable recyclable polyester containing double bond side group 青岛科技大学 2023-04-21 CN claimed
WO-2023061463-A1 NOVEL PYRIMIDOPYRIDINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF 广东东阳光药业有限公司 2023-04-20 WO claimed
CN-115974896-A Novel pyrimidopyridine compounds, pharmaceutical compositions thereof and uses thereof 广东东阳光药业有限公司 2023-04-18 CN claimed
CN-114349939-B Rapid preparation method of recyclable bio-based polyester 青岛科技大学 2023-04-07 CN claimed
CN-115286651-A Method for preparing 2-boron-allyl boride through copper-catalyzed boron-amido-allene hydroboration reaction 南京理工大学 2022-11-04 CN claimed
US-4910221-A Having a halogen group in position 4 of ring BAYER AKTIENGESELLSCHAFT (DE) 1990-03-20 US claimed
US-4886832-A Fungicidal benzaldoxime derivatives BAYER AKTIENGESELLSCHAFT (DE) 1989-12-12 US claimed
US-4744819-A 4-oxo pyridinecarboxamide derivatives as plant growth regulators DAICEL CHEMICAL INDUSTRIES LTD. (JP) 1988-05-17 US claimed
US-4743609-A ANTIULCER BANYU PHARMACEUTICAL CO., LTD. (JP) 1988-05-10 US claimed
US-4725306-A Pyridinecarboxamide plant growth inhibitors DAICEL CHEMICAL INDUSTRIES LTD. (JP) 1988-02-16 US claimed
US-4647579-A Circulation active novel substituted 4-hydroxy-benzopyrans BAYER AKTIENGESELLSCHAFT (DE) 1987-03-03 US claimed
US-4331597-A AMOXYCILLIN DERIVATIVES MEIJI SEIKA KAISHA, LTD. (JP) 1982-05-25 US claimed
US-4066438-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-01-03 US claimed
US-4021421-A ENZYME INDUCING ACTIVITY RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1977-05-03 US claimed
US-3948877-A POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US claimed