Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23701486 | 1.00 | DRD4 (0.44) | DRD4EEDRORCHTR2AHTR2C | |
| SCHEMBL9042636 | 0.83 | SMN1; SMN2 (0.52) | DRD4RORCSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1749014 | 0.83 | SMN1; SMN2 (0.52) | DRD4RORCSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27399995 | 0.82 | DRD4 (0.49) | DRD4EEDRORCHTR2AHTR2C | |
| SCHEMBL23701452 | 0.82 | DRD4 (0.49) | DRD4EEDRORCHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL1749238 | 0.81 | SMN1; SMN2 (0.51) | DRD4RORCSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27400032 | 0.79 | POLB (0.51) | RORCSMN1; SMN2KDM4EBCHEALDH1A1 | |
| SCHEMBL23701404 | 0.76 | GAA (0.46) | DRD4RORCKDM4EPTGS2BCHE | |
| SCHEMBL27400009 | 0.76 | GAA (0.46) | DRD4RORCKDM4EPTGS2BCHE | |
| SCHEMBL23701396 | 0.76 | KMT2A (0.55) | KDM4EALDH1A1MAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018029-B2 | Hexahydropyrrolo[3,4-c]pyrrole derivatives useful as LOX inhibitors | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2024-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12018029-B2 | Hexahydropyrrolo[3,4-c]pyrrole derivatives useful as LOX inhibitors | LOX, LOXL1, LOXL3 | DRD4 953/4885EED 4552/4885RORC 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.