SCHEMBL274002

SCHEMBL274002

Nc1cc(Cl)ncn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11901592 0.97
Methane SCHEMBL15561212 0.97
SCHEMBL29136970 0.97 KMO (0.44)
Isopropylamine SCHEMBL8601026 0.89 KMO (0.39)
Adamantane SCHEMBL2190545 0.87 KMO (0.38)
SCHEMBL125453 0.78
SCHEMBL31051471 0.78
Water SCHEMBL9644118 0.76
Hydrochloric Acid SCHEMBL1313405 0.76
SCHEMBL30296887 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
CN-110563657-B 1- (2, 6-Dichlorophenyl) -3-substituted urea colon cancer inhibitor and preparation and application thereof 温州医科大学 2024-05-03 CN claimed
CN-115215806-B Synthesis method of sulfanilamide-6-methoxypyrimidine 江苏天和制药有限公司 2024-03-29 CN claimed
CN-110283130-B 1- (2, 5-dimethoxy phenyl) -3-substituted urea colon cancer inhibitor and preparation and application thereof 温州医科大学 2023-12-19 CN claimed
CN-110396066-B 1- (3, 5-dimethoxy phenyl) -3-substituted urea colon cancer inhibitor and preparation and application thereof 温州医科大学 2023-12-19 CN claimed
CN-115215806-A Method for synthesizing sulfanilamide-6-methoxypyrimidine 江苏天和制药有限公司 2022-10-21 CN claimed
CN-110981816-B Synthesis method of 4-amino-2, 6-dimethoxypyrimidine 天和药业股份有限公司 2022-07-05 CN claimed
US-20220195497-A1 HYBRIDIZING all-LNA OLIGONUCLEOTIDES ROCHE DIAGNOSTICS OPERATIONS, INC. 2022-06-23 US claimed
EP-3980554-A1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2022-04-13 EP claimed
CN-109053592-A 1- (2,5- Dimethoxyphenyl) -3- (substituted pyrimidines -4- base) carbamide compounds and its preparation and application 温州医科大学 2018-12-21 CN claimed
CN-109053593-A 1- (2,6- chlorphenyl) -3- (substituted pyrimidines -4- base) carbamide compounds and its preparation and application 温州医科大学 2018-12-21 CN claimed
CN-109053594-A 1- (3,5- Dimethoxyphenyl) -3- (substituted pyrimidines -4- base) carbamide compounds and its preparation and application 温州医科大学 2018-12-21 CN claimed
CN-103865290-B Fluorine boron fluorescence dye and its preparation method and application ANHUI NORMAL UNIVERSITY (CN) 2016-03-30 CN claimed
CN-103865290-A Fluorine-boron fluorescent dye as well as preparation method and application thereof UNIV ANHUI NORMAL 2014-06-18 CN claimed
CN-103012283-A Preparation method of 4-aminopyrimidine DALIAN QIKAI MEDICAL TECHNOLOGY CO LTD 2013-04-03 CN claimed
WO-2012158197-A2 COMPOUNDS USEFUL AS AKT/PKB MODULATORS AND USES THEREOF LYNDOR BIOSCIENCES L.L.C. (US) 2012-11-22 WO claimed
CN-102516182-A Preparation method for 4-amino-6-alkoxyl pyrimidine compounds YWK CHEMICALS TAICANG CO LTD 2012-06-27 CN claimed
CN-101363779-B Method for enhancing ionization efficiency of peptide segment UNIV FUDAN 2011-07-27 CN claimed
CN-101363779-A Method for enhancing ionization efficiency of peptide segment UNIV FUDAN (CN) 2009-02-11 CN claimed