⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28153591 | 0.96 | MEN1 (0.40) | — | |
| Methylene Chloride SCHEMBL27947432 | 0.90 | MEN1 (0.38) | — | |
| SCHEMBL29136970 | 0.83 | KMO (0.44) | — | |
| Acetaldehyde SCHEMBL28232456 | 0.83 | NPC1 (0.35) | — | |
| Isopropyl Alcohol SCHEMBL28207243 | 0.83 | NPC1 (0.35) | — | |
| Chlorobenzene SCHEMBL27930649 | 0.81 | TSHR (0.55) | — | |
| Bicarbonate SCHEMBL28202844 | 0.81 | KMO (0.33) | — | |
| SCHEMBL4146204 | 0.78 | — | — | |
| SCHEMBL9970864 | 0.78 | — | — | |
| SCHEMBL1851665 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12275728-B2 | O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranosidase inhibitors | BIOGEN MA INC. (US) | 2025-04-15 | — | — | US | disclosed |
| US-12180205-B2 | O-glycoprotein-2-acetamido-2-deoxy-3-d-glucopyranosidase inhibitors | BIOGEN MA INC. (US) | 2024-12-31 | — | — | US | disclosed |
| US-20240308995-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. | 2024-09-19 | — | — | US | disclosed |
| CN-113166137-B | O-glycoprotein-2-acetamido-2-deoxy-3-D-glucopyranoside enzyme inhibitors | 比奥根MA公司 | 2024-08-16 | — | — | CN | disclosed |