Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489834 | 0.80 | TSHR (0.43) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL8743225 | 0.79 | ALDH1A1 (0.39) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL10538170 | 0.74 | ALDH1A1 (0.39) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL3709231 | 0.72 | ALDH1A1 (0.37) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL3701495 | 0.69 | ALDH1A1 (0.34) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL10660530 | 0.69 | ALDH1A1 (0.35) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL2727312 | 0.67 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL13862591 | 0.67 | MEN1 (0.36) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL377343 | 0.67 | ZDHHC20 (0.39) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL14880 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |