Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | B3GNT2 | Q9NY97 | 3/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402732 | 1.00 | PDE2A (0.59) | PDE2ATAS1R3TAS1R1SMYD3CTSK | |
| SCHEMBL12658565 | 0.81 | SMYD3 (0.49) | SMYD3IMPDH2KDM4EALDH1A1B3GNT2 | |
| SCHEMBL27402577 | 0.80 | ALDH1A1 (0.57) | PDE2ASMYD3IMPDH2ALDH1A1HPGD | |
| SCHEMBL27402490 | 0.80 | B3GNT2 (0.60) | PDE2ATAS1R3TAS1R1SMYD3IMPDH2 | |
| SCHEMBL27402731 | 0.79 | SMYD3 (0.46) | SMYD3IMPDH2B3GNT2MAPTMAPK11 | |
| SCHEMBL27402835 | 0.78 | NR1H4 (0.62) | PDE2ASMYD3IMPDH2B3GNT2MAPT | |
| SCHEMBL27400717 | 0.78 | TAS1R3 (0.60) | PDE2ATAS1R3TAS1R1IMPDH2ALDH1A1 | |
| SCHEMBL19531859 | 0.77 | TAS1R3 (0.68) | TAS1R3TAS1R1SMYD3CTSKKDM4E | |
| SCHEMBL27402404 | 0.77 | PDE2A (0.55) | PDE2A | |
| SCHEMBL27401308 | 0.77 | PDE2A (0.55) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024117179-A1 | KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | ALIVEXIS, INC. (JP) | 2024-06-06 | — | — | WO | disclosed |