Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | MC3R | P41968 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740206 | 0.86 | CTSB (0.54) | CTSBCAPN1CTSL | |
| SCHEMBL14623960 | 0.86 | CTSB (0.54) | CTSBCAPN1CTSL | |
| SCHEMBL25382819 | 0.79 | CAPN1 (0.47) | CTSBCAPN1 | |
| SCHEMBL3989376 | 0.79 | CAPN1 (0.47) | CTSBCAPN1 | |
| SCHEMBL2739915 | 0.79 | ALDH1A1 (0.54) | — | |
| SCHEMBL2267800 | 0.78 | TDP1 (0.43) | CTSBCAPN1NOS3NOS1NOS2 | |
| SCHEMBL2268714 | 0.78 | TDP1 (0.43) | CTSBCAPN1NOS3NOS1NOS2 | |
| SCHEMBL15936999 | 0.78 | KDM4E (0.45) | MC4RMC3RCTSL | |
| SCHEMBL20204691 | 0.77 | CTSC (0.58) | CTSBCAPN1CTSL | |
| SCHEMBL20204693 | 0.77 | CTSC (0.58) | CTSBCAPN1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863832-B1 | AGE INHIBITORS | CENTRE NAT RECH SCIENT (FR) | 2012-01-04 | — | — | EP | disclosed |
| WO-2006103274-A9 | AGE INHIBITORS | PHARMAMENS (FR) | 2007-01-18 | — | — | WO | disclosed |