Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.69 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.69 |
| ▸ | F10 | P00742 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858374 | 0.83 | NOD2 (0.80) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL4798323 | 0.81 | NOD2 (0.85) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL6302610 | 0.81 | NOD2 (0.84) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL5213582 | 0.80 | NOD2 (0.78) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL6706704 | 0.80 | NOD2 (0.82) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL5421098 | 0.80 | NOD2 (0.82) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL12948823 | 0.80 | NOD2 (0.82) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL6307843 | 0.78 | NOD2 (0.74) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL4198841 | 0.77 | NOD2 (0.77) | NOD2NOD1F10KMT2AMEN1 | |
| SCHEMBL6436885 | 0.77 | NOD2 (0.77) | NOD2NOD1F10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1096513-A | Endothelin-receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1994-12-21 | — | — | CN | disclosed |