SCHEMBL27404584

SCHEMBL27404584

[O]CCN1c2ccccc2Oc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.46
P2RX4 Q99571 8/20 0.46
PIM1 P11309 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HDAC3 O15379 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
HDAC4 P56524 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
HDAC1 Q13547 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3964920 0.83 P2RX4 (0.48) SIGMAR1P2RX4HDAC3HDAC6P2RX1
SCHEMBL29759083 0.79 SIGMAR1 (0.50) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL2595930 0.79 SIGMAR1 (0.46) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL14464161 0.79 SIGMAR1 (0.46) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL30216960 0.79 SIGMAR1 (0.46) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL24631312 0.79 SIGMAR1 (0.46) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL32685462 0.79 SIGMAR1 (0.46) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL7696530 0.79 SIGMAR1 (0.50) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL16519524 0.78 P2RX4 (0.44) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL179725 0.77 MAPT (0.60) SIGMAR1P2RX4MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1130483-C Fabric treated with cellulose and oxidoreductase NOVOZYMES AS (DK) 2003-12-10 CN claimed
CN-1078279-C Bleaching process comprising the use of a phenol oxidizing enzyme, a hydrogen peroxide source and an enhancing agent NOVO CHIMAIDS AS (DK) 2002-01-23 CN claimed
CN-1218524-A Fabric treated with cellulose and oxidoreductase NOVO NORDISK AS (DK) 1999-06-02 CN claimed
CN-1161723-A Bleaching method by use of phenol oxidization enzyme, hydrogen peroxide source and enhancing agent NOVO NORDISK AS (DK) 1997-10-08 CN claimed
CN-1078279-C Bleaching process comprising the use of a phenol oxidizing enzyme, a hydrogen peroxide source and an enhancing agent NOVO CHIMAIDS AS (DK) 2002-01-23 CN disclosed
CN-1161723-A Bleaching method by use of phenol oxidization enzyme, hydrogen peroxide source and enhancing agent NOVO NORDISK AS (DK) 1997-10-08 CN disclosed