SCHEMBL2595930

SCHEMBL2595930

OCCN1c2ccccc2Oc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.46
P2RX4 Q99571 8/20 0.46
PIM1 P11309 3/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
HDAC3 O15379 1/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
HDAC4 P56524 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
HDAC1 Q13547 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30216960 1.00 SIGMAR1 (0.46) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL1366285 0.83 HDAC3 (0.61) P2RX4MEN1KMT2AHDAC3TUBB4A
SCHEMBL7717760 0.83 PIM1 (0.51) SIGMAR1PIM1MEN1KMT2ATDP1
SCHEMBL3964924 0.83 P2RX4 (0.48) SIGMAR1P2RX4HDAC3TUBB4ATUBB
SCHEMBL5711025 0.82 HTR2A (0.47) SIGMAR1PIM1MEN1KMT2ATDP1
SCHEMBL29833637 0.82 HTR2A (0.47) SIGMAR1PIM1MEN1KMT2ATDP1
SCHEMBL9419616 0.82 HTR1A (0.62) SIGMAR1PIM1MEN1KMT2ATDP1
SCHEMBL24631312 0.79 SIGMAR1 (0.46) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL7696530 0.79 SIGMAR1 (0.50) SIGMAR1P2RX4PIM1MEN1KMT2A
SCHEMBL32685462 0.79 SIGMAR1 (0.46) SIGMAR1P2RX4PIM1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707637-B1 ENHANCEMENT OF LACCASE REACTIONS NOVOZYMES AS (DK) 2005-11-02 EP claimed
EP-1137391-B1 METHOD FOR TREATING HAIR NOVOZYMES AS (DK) 2004-11-03 EP claimed
US-6572843-B1 Combining permanent dyeing and straightening; applying to reduced hair an oxidizing enzyme (Laccase), a mediator, and a chemical oxidizing agent that produces hydrogen peroxide NOVOZYMES, A/S (DK) 2003-06-03 US claimed
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 US claimed
WO-2002034733-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF 2-[PHENOXAZIN-10-YL]ETHYLMETHANE SULPHONATE DR. REDDY'S RESEARCH FOUNDATION (IN) 2002-05-02 WO claimed
CN-1334718-A Hair treatment method NOVOZYMES AS (DK) 2002-02-06 CN claimed
US-20020007524-A1 Contacting fibers in a dry state with an oxidoreductase and a dye precursor; reduced hair damage NOVOZYMES A/S (DK) 2002-01-24 US claimed
EP-1137391-A1 METHOD FOR TREATING HAIR Novozymes A/S (DK) 2001-10-04 EP claimed
EP-1076494-A1 RE-FORMATION OF KERATINOUS FIBRE CROSS LINKS Novozymes A/S (DK) 2001-02-21 EP claimed
JP-2000512267-A 2000-09-19 JP claimed
WO-1999058013-A1 RE-FORMATION OF KERATINOUS FIBRE CROSS LINKS NOVO NORDISK A/S (DK) 1999-11-18 WO claimed
US-5951714-A Enzymatic discharge printing of dyed textiles NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) 1999-09-14 US claimed
EP-0912097-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1999-05-06 EP claimed
US-5899212-A CLEAVAGE OF DISULFIDE BONDS, OXIDOREDUCTASE NOVO NORDISK A/S (DK) 1999-05-04 US claimed
US-5885304-A AROMATIC COMPOUNDS CONTAINING AT LEAST TWO RINGS, AT LEAST ONE SUBSTITUTED WITH NITROGEN OXYGEN, OR SULFUR NOVO NORDISK A/S (DK) 1999-03-23 US claimed
WO-1998046820-A1 ENZYMATIC DISCHARGE PRINTING OF DYED TEXTILES NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) 1998-10-22 WO claimed
US-5795855-A DETERGENTS NOVO NORDISK A/S 1998-08-18 US claimed
WO-1997042825-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1997-11-20 WO claimed
EP-0707637-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1996-04-24 EP claimed
WO-1995001426-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1995-01-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020007524-A1 Contacting fibers in a dry state with an oxidoreductase and a dye precursor; reduced hair damage KRT18, CYB5R3, ADH7 SIGMAR1 4632/4885P2RX4 4078/4885PIM1 4715/4885
US-20020119136-A1 Antimicrobial peroxidase compositions LPO, MPO, GPX4 SIGMAR1 1531/4885P2RX4 3934/4885PIM1 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.