Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474110 | 0.96 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL12143438 | 0.92 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL27402068 | 0.84 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL27920137 | 0.83 | LOXL2 (0.47) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL1799441 | 0.83 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL27425792 | 0.83 | LOXL2 (0.64) | RAB9ASMN1; SMN2MAPTCA12CA1 | |
| SCHEMBL27420028 | 0.82 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL27536387 | 0.82 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL20295092 | 0.81 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2MAPTHTT | |
| SCHEMBL27406895 | 0.81 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1232505-C | Substituted sulfonamido (thio) carbonyl compounds | BAYER AG (DE) | 2005-12-21 | — | — | CN | disclosed |
| CN-1439631-A | Substituted sulfonamido (thio) carbonyl compounds | BAYER AG (DE) | 2003-09-03 | — | — | CN | disclosed |
| CN-1105717-C | Substituted sulfonamido (thio) carbonyl compounds | BAYER AG (DE) | 2003-04-16 | — | — | CN | disclosed |
| CN-1207099-A | Substituted sulfonamido (thio) carbonyl compounds | BAYER AG (DE) | 1999-02-03 | — | — | CN | disclosed |