Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25C | P30307 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843728 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| SCHEMBL7444251 | 0.79 | KDM4E (0.53) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| SCHEMBL29643419 | 0.79 | KDM4E (0.53) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| SCHEMBL15568024 | 0.79 | KDM4E (0.53) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| Hydrochloric Acid SCHEMBL2125919 | 0.78 | KDM4E (0.51) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| Hydrochloric Acid SCHEMBL809035 | 0.78 | KDM4E (0.51) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| SCHEMBL28956635 | 0.77 | PSMB5 (0.52) | ALDH1A1CYP2C19CA12CA14CA2 | |
| Hydrochloric Acid SCHEMBL808851 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| SCHEMBL20827331 | 0.75 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP1A2CYP2C19KDM4E | |
| SCHEMBL8166236 | 0.75 | KMT2A (0.46) | ALDH1A1CYP2C19GAACA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | DICE MOLECULES SV, INC. | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | ITGB1, ITGA1, ITGAV | ALDH1A1 858/4885HPGD 2690/4885CYP1A2 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.