Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27405870 | 0.82 | MEN1 (0.46) | MAPTNPC1ALDH1A1KDM4EKMT2A | |
| SCHEMBL27405874 | 0.82 | LMNA (0.50) | MAPTSMN1; SMN2HPGDPOLBALDH1A1 | |
| SCHEMBL27405477 | 0.82 | LMNA (0.60) | SMN1; SMN2HPGDALDH1A1KDM4EKMT2A | |
| SCHEMBL27405479 | 0.81 | TDP1 (0.58) | MAPTSMN1; SMN2RAB9APOLBALDH1A1 | |
| SCHEMBL27405594 | 0.79 | RXFP1 (0.60) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL27406004 | 0.78 | LMNA (0.40) | MAPTSMN1; SMN2RAB9APKMPOLB | |
| SCHEMBL27406002 | 0.77 | ALDH1A1 (0.42) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL27406001 | 0.77 | LMNA (0.48) | SMN1; SMN2POLBALDH1A1KMT2ATDP1 | |
| SCHEMBL27398877 | 0.77 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EKMT2ATDP1 | |
| SCHEMBL27406110 | 0.77 | LMNA (0.56) | SMN1; SMN2POLBALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112918-A1 | RNA DEGRADERS AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |