SCHEMBL27407486

SCHEMBL27407486

[CH2]CCN1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HEXA P06865 6/20 0.69
HEXB P07686 6/20 0.69
OGA O60502 1/20 0.67
KDM4E B2RXH2 4/20 0.63
ALDH1A1 P00352 4/20 0.63
MAPT P10636 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
GAA P10253 1/20 0.63
RAB9A P51151 1/20 0.63
CYP1B1 Q16678 1/20 0.62
SIRT1 Q96EB6 3/20 0.61
KMT2A Q03164 3/20 0.59
MEN1 O00255 2/20 0.59
POLB P06746 2/20 0.59
NR1I2 O75469 1/20 0.59
AHR P35869 1/20 0.59
RAD52 P43351 1/20 0.59
RCE1 Q9Y256 1/20 0.59
HSD17B10 Q99714 2/20 0.57
HPGD P15428 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5814604 0.85 CYP1B1 (0.67) HEXAHEXBOGAKDM4EALDH1A1
SCHEMBL9626265 0.85 HEXA (0.83) HEXAHEXBOGAKDM4EALDH1A1
SCHEMBL9625535 0.83 HEXA (0.81) HEXAHEXBOGAKDM4EALDH1A1
SCHEMBL9625395 0.83 HEXA (0.81) HEXAHEXBOGAKDM4EALDH1A1
SCHEMBL9625779 0.83 HEXA (0.81) HEXAHEXBOGAKDM4EALDH1A1
SCHEMBL9625518 0.83 HEXA (0.81) HEXAHEXBOGAKDM4EALDH1A1
SCHEMBL1553739 0.82 GLS (0.61) ALDH1A1MAPTSMN1; SMN2RAB9ACYP1A2
SCHEMBL3985857 0.81 HEXA (0.69) HEXAHEXBOGAKDM4EALDH1A1
SCHEMBL4997995 0.81 HEXA (1.00) HEXAHEXBOGAKDM4EALDH1A1
SCHEMBL10396736 0.81 HEXA (0.69) HEXAHEXBOGAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102939140-A Functionalized substrates with aromatic stacking properties DIONEX CORP 2013-02-20 CN disclosed
CN-101627043-A Silane compound, production method thereof, and resin composition containing silane compound NIPPON CATALYTIC CHEM IND 2010-01-13 CN disclosed
CN-1094036-A Novel asymmetrical commutable bis-naphthalimides KNOLL AG (DE) 1994-10-26 CN disclosed