Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.49 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.49 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740986 | 0.86 | MEN1 (0.56) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL13128959 | 0.84 | KDM4E (0.54) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2741006 | 0.83 | MEN1 (0.55) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2740985 | 0.83 | MEN1 (0.54) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2740993 | 0.83 | MAPT (0.55) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2741007 | 0.82 | MEN1 (0.58) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2740990 | 0.82 | L3MBTL1 (0.57) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2740948 | 0.82 | L3MBTL1 (0.55) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2740989 | 0.81 | MEN1 (0.52) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL2741013 | 0.80 | MEN1 (0.58) | MEN1KMT2AHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088772-B2 | Sulfonamides and their use as a medicament | THE GENETICS COMPANY, INC. (CH) | 2012-01-03 | — | — | US | disclosed |
| US-8088772-B2 | Sulfonamides and their use as a medicament | THE GENETICS COMPANY, INC. (CH) | 2012-01-03 | — | — | US | disclosed |