Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 12/20 | 0.53 |
| ▸ | GAA | P10253 | 7/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740949 | 0.91 | MEN1 (0.54) | MEN1KMT2ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL2741006 | 0.83 | MEN1 (0.55) | MEN1KMT2ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL2740951 | 0.83 | MEN1 (0.57) | MEN1KMT2ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL15202236 | 0.81 | MAPT (0.63) | MEN1KMT2ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL15202237 | 0.81 | MAPT (0.63) | MEN1KMT2ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL2740990 | 0.81 | L3MBTL1 (0.57) | MEN1KMT2ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL2740948 | 0.81 | L3MBTL1 (0.55) | MEN1KMT2ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL2740986 | 0.81 | MEN1 (0.56) | MEN1KMT2ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL2740993 | 0.80 | MAPT (0.55) | MEN1KMT2ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL2740987 | 0.80 | MEN1 (0.55) | MEN1KMT2ARAB9AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088772-B2 | Sulfonamides and their use as a medicament | THE GENETICS COMPANY, INC. (CH) | 2012-01-03 | — | — | US | disclosed |