Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ACLY | P53396 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28098669 | 0.90 | MAPT (0.46) | ALDH1A1MAPTKDM4ELMNAGAA | |
| SCHEMBL27443326 | 0.78 | CYP1A2 (0.39) | ALDH1A1MAPTKDM4ELMNAGAA | |
| SCHEMBL27646023 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1MAPTKDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL27410031 | 0.76 | TSHR (0.41) | ALDH1A1MAPTKDM4ELMNAGAA | |
| SCHEMBL28210773 | 0.76 | NPC1 (0.49) | ALDH1A1MAPTKDM4ERAB9AMEN1 | |
| SCHEMBL28242784 | 0.75 | BCL2L1 (0.53) | ALDH1A1MAPTKDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL27480011 | 0.75 | NPC1 (0.48) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL27734209 | 0.73 | KDM4E (0.51) | ALDH1A1MAPTKDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL28489029 | 0.71 | ACLY (0.49) | ALDH1A1MAPTKDM4ELMNAACLY | |
| SCHEMBL25791893 | 0.71 | CA1 (0.51) | ALDH1A1MAPTKDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1252066-C | Pyridazine-3-one derivatives, their use, and intermediate preparing them | SUMITOMO CHEMICAL CO (JP) | 2006-04-19 | — | — | CN | disclosed |
| CN-1491949-A | Pyridazine-3-one derivatives, their use, and intermediate preparing them | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-04-28 | — | — | CN | disclosed |
| CN-1117083-C | Pyridazin-3-one derivatives, their use, and intermediates for their preparation | SUMITOMO CHEMICAL CO (JP) | 2003-08-06 | — | — | CN | disclosed |
| CN-1202157-A | Pyridazin-3-one derivatives, their use, and intermediates for their preparation | SUMITOMO CHEMICAL CO (JP) | 1998-12-16 | — | — | CN | disclosed |