Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | GFER | P55789 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410033 | 0.90 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4EGAAGFER | |
| SCHEMBL25791893 | 0.82 | CA1 (0.51) | MAPTALDH1A1KDM4EGAALMNA | |
| Hydrochloric Acid SCHEMBL16797134 | 0.81 | PTGER4 (0.50) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL27443326 | 0.78 | CYP1A2 (0.39) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL27646023 | 0.77 | SMN1; SMN2 (0.44) | MAPTALDH1A1KDM4EGAAHPGD | |
| Hydrochloric Acid SCHEMBL28098668 | 0.76 | PTGER4 (0.41) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL28210773 | 0.76 | NPC1 (0.49) | MAPTALDH1A1KDM4ERAB9AMEN1 | |
| SCHEMBL28242784 | 0.75 | BCL2L1 (0.53) | MAPTALDH1A1KDM4EGAALMNA | |
| Hydrochloric Acid SCHEMBL27480011 | 0.75 | NPC1 (0.48) | ALDH1A1KDM4ERAB9AMEN1KMT2A | |
| SCHEMBL27734209 | 0.73 | KDM4E (0.51) | MAPTALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980364-A | Bicyclic heteroaryl indole analogs useful as ROR γ modulators | 格兰马克药品股份有限公司 | 2016-09-28 | — | — | CN | disclosed |