Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2057187 | 0.94 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL6629548 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL27386707 | 0.81 | TSHR (0.53) | MEN1KMT2APOLBTSHRAOC3 | |
| SCHEMBL3063325 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL13306986 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL12305028 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL10192138 | 0.76 | ALDH1A1 (0.49) | ALDH1A1LMNAPOLBTSHRCA2 | |
| SCHEMBL1243447 | 0.76 | CA2 (0.64) | ALDH1A1MEN1KMT2ALMNATSHR | |
| SCHEMBL8930273 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL15672917 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1221533-C | Heterobicyclic sulfonamide derivative and sulfonic ester derivative | EISAI CO LTD (JP) | 2005-10-05 | — | — | CN | disclosed |
| CN-1491941-A | Heterobicyclic sulfonamide derivative and sulfonic ester derivative | ������������ʽ���� | 2004-04-28 | — | — | CN | disclosed |
| CN-1079097-C | Heterobicyclic sulfonamide derivatives and sulfonate derivatives | EISAI CO LTD (JP) | 2002-02-13 | — | — | CN | disclosed |
| CN-1114506-A | Heterobicyclic sulfonamide derivatives and sulfonate derivatives | EISAI CO LTD (JP) | 1996-01-03 | — | — | CN | disclosed |