SCHEMBL27410254

SCHEMBL27410254

CCN1CSc2ccccc21.O=S(=O)(O)c1ccc2ncccc2c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ HTR7 P34969 10/20 0.45
▸ HTR6 P50406 7/20 0.45
▸ HTR1A P08908 2/20 0.40
▸ HTR2A P28223 2/20 0.40
▸ NAMPT P43490 2/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ CHRM5 P08912 1/20 0.38
▸ NPY5R Q15761 1/20 0.38
▸ BCAT1 P54687 1/20 0.37
▸ CHRM1 P11229 1/20 0.36
▸ GBA1 P04062 1/20 0.36
▸ F10 P00742 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL27732328 0.82 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2
Sulfuric Acid SCHEMBL6232322 0.77 POLB (0.40) ALDH1A1LMNA
SCHEMBL7108207 0.76 MAPT (0.40) ALDH1A1LMNA
SCHEMBL363013 0.76 ALDH1A1 (0.37) ALDH1A1LMNASMN1; SMN2
Sulfuric Acid SCHEMBL7586602 0.76 POLB (0.39) ALDH1A1LMNA
SCHEMBL6443612 0.76 ALDH1A1 (0.55) HTR7HTR6NAMPTALDH1A1LMNA
SCHEMBL29819245 0.76 ALDH1A1 (0.55) HTR7HTR6NAMPTALDH1A1LMNA
Ammonia Solution, Strong SCHEMBL2675711 0.75 ALDH1A1 (0.36) ALDH1A1LMNASMN1; SMN2
Ammonia Solution, Strong SCHEMBL2675714 0.75 ALDH1A1 (0.36) ALDH1A1LMNASMN1; SMN2
Ammonia Solution, Strong SCHEMBL7544721 0.75 ALDH1A1 (0.36) ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111818919-A Imipritone for glioma 昂克希尔迪克斯有限公司 2020-10-23 — — CN disclosed
CN-101631854-B Laccase for pulp bio-bleaching VERENIUM CORP US 2012-08-29 — — CN disclosed
CN-102634491-A Laccase for pulp bio-bleaching VERENIUM CORP 2012-08-15 — — CN disclosed
CN-102573919-A Disulfide-linked polyethylene glycol/peptide conjugates for nucleic acid transfection CUREVAC GMBH 2012-07-11 — — CN disclosed
CN-101705277-B Primers for detecting telomerase activity UNIV NANKAI 2012-05-23 — — CN disclosed
CN-102216776-A Urinary biomarkers for predicting long-term dialysis UNIV PITTSBURGH 2011-10-12 — — CN disclosed
CN-102123733-A Compositions comprising complex and naked RNAs for providing or enhancing an immunostimulatory response in a mammal and uses thereof CUREVAC GMBH 2011-07-13 — — CN disclosed
CN-101977935-A Methods and compositions for treating and monitoring treatment of il-13-associated disorders WYETH CORP 2011-02-16 — — CN disclosed
CN-101796191-A complexes of rna and cationic peptides for transfection and for immunostimulation CUREVAC GMBH 2010-08-04 — — CN disclosed
CN-101705277-A Primers for detecting activity of telomerase UNIV NANKAI 2010-05-12 — — CN disclosed
CN-101636415-A Be used for enrichment, remove and detect the ways and means of gram positive bacterium BIOMERIEUX SA 2010-01-27 — — CN disclosed
CN-101631854-A Laccase for pulp bio-bleaching VERENIUM CORP 2010-01-20 — — CN disclosed
CN-1102974-C Multi-component system for modifying, degrading or bleaching lignin, lignin-containing materials or similar substances and processes for its use CONSORTIUM ELEKTROCHEM IND (DE) 2003-03-12 — — CN disclosed
CN-1240008-A Multicomponent system for modifying, degrading or bleaching lignin, lignin-containing materials or the like and method for the use thereof ELEKTOCHEMISCHE IND GMBH (DE) 1999-12-29 — — CN disclosed
CN-1232384-A Diaminobenzoic acid derivatives as dye precursors NOVO NORDISK AS (DK) 1999-10-20 — — CN disclosed
CN-1189556-A Multi-component system for modifying, degrading or bleaching lignin, lignin-containing materials or similar substances and processes for its use CONSORTIUM ELEKTROCHEM IND (DE) 1998-08-05 — — CN disclosed
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