Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410343 | 0.83 | CA1 (0.53) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL27410339 | 0.83 | CA1 (0.51) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL27410348 | 0.77 | CA1 (0.33) | CA1CA2MAPTTDP1KDM4E | |
| SCHEMBL27410602 | 0.77 | CA1 (0.42) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL21163027 | 0.77 | CA1 (0.43) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL20067639 | 0.77 | CA1 (0.64) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL16424832 | 0.76 | SIRT5 (0.43) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL16424839 | 0.74 | CA1 (0.52) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL25945505 | 0.73 | CA1 (0.44) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL22239381 | 0.73 | TDP1 (0.46) | CA1CA2SIRT5MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123914-A1 | PROCESS FOR MAKING ANTIBODY-DRUG CONJUGATES | MERCK SHARP & DOHME LLC (US) | 2024-06-13 | — | — | WO | disclosed |