Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529519 | 0.83 | CA1 (0.45) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL20529521 | 0.83 | CA1 (0.45) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL31726507 | 0.82 | CA1 (0.50) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL24297227 | 0.81 | CA2 (0.41) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL29078274 | 0.81 | CA2 (0.41) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL21163027 | 0.80 | CA1 (0.43) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL20529545 | 0.80 | CA1 (0.41) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL20529548 | 0.80 | CA1 (0.41) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL20067639 | 0.80 | CA1 (0.64) | CA1CA2SIRT5MAPTTDP1 | |
| SCHEMBL16424832 | 0.80 | SIRT5 (0.43) | CA1CA2SIRT5MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131219-A1 | CONJUGATES, COMPOSITIONS AND METHODS OF USE | VIRTUOSO BINCO, INC. (US) | 2023-07-13 | — | — | WO | disclosed |