SCHEMBL2741114

SCHEMBL2741114

Cc1ccc(N(C)c2ccc(/C=N/N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.48
LMNA P02545 3/20 0.48
MAPK1 P28482 2/20 0.48
GFER P55789 1/20 0.48
MEN1 O00255 6/20 0.47
KMT2A Q03164 6/20 0.47
KDM4E B2RXH2 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MAPT P10636 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
NFKB1 P19838 1/20 0.47
CASP3 P42574 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
ALDH1A1 P00352 5/20 0.46
CYP1A2 P05177 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12637395 0.93 SMN1; SMN2 (0.53) SMN1; SMN2LMNAMAPK1GFERMEN1
SCHEMBL1199116 0.89 MEN1 (0.48) SMN1; SMN2LMNAMAPK1MEN1KMT2A
SCHEMBL12677649 0.89 MEN1 (0.48) SMN1; SMN2LMNAMAPK1MEN1KMT2A
SCHEMBL359917 0.89 MEN1 (0.48) SMN1; SMN2LMNAMAPK1MEN1KMT2A
SCHEMBL1199117 0.89 MEN1 (0.48) SMN1; SMN2LMNAMAPK1MEN1KMT2A
SCHEMBL1199348 0.89 MEN1 (0.48) SMN1; SMN2LMNAMAPK1MEN1KMT2A
SCHEMBL12083950 0.84 MEN1 (0.45) SMN1; SMN2LMNAMAPK1MEN1KMT2A
SCHEMBL331931 0.83 ALDH1A1 (0.62) SMN1; SMN2MAPK1MEN1KMT2AKDM4E
SCHEMBL331930 0.83 ALDH1A1 (0.62) SMN1; SMN2MAPK1MEN1KMT2AKDM4E
SCHEMBL15600309 0.82 CYP2A6 (0.46) SMN1; SMN2LMNAMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8568946-B2 Electrophotographic photoreceptor and image formation device comprising same SHARP KABUSHIKI KAISHA (JP) 2013-10-29 US disclosed
US-8568946-B2 Electrophotographic photoreceptor and image formation device comprising same SHARP KABUSHIKI KAISHA (JP) 2013-10-29 US disclosed
US-20120003577-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMATION DEVISE COMPRISING SAME SHARP KABUSHIKI KAISHA (JP) 2012-01-05 US disclosed
US-20120003577-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMATION DEVISE COMPRISING SAME SHARP KABUSHIKI KAISHA (JP) 2012-01-05 US disclosed