Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9043289 | 0.82 | KMT2A (0.57) | ALDH1A1KMT2AGAAMAPTP2RX7 | |
| Bicarbonate SCHEMBL7620822 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KMT2AGAAMAPTP2RX7 | |
| Bicarbonate SCHEMBL7618943 | 0.70 | ALDH1A1 (0.70) | ALDH1A1KMT2AGAAMAPTP2RX7 | |
| Bicarbonate SCHEMBL9046253 | 0.70 | KMT2A (0.62) | ALDH1A1KMT2AGAAMAPTP2RX7 | |
| SCHEMBL14826518 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KMT2AGAAMAPTP2RX7 | |
| SCHEMBL12851348 | 0.70 | TP53 (0.67) | ALDH1A1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4299881 | 0.70 | SMN1; SMN2 (0.65) | ALDH1A1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL27440934 | 0.69 | SIGMAR1 (0.50) | ALDH1A1KMT2AMAPTP2RX7RAB9A | |
| SCHEMBL23619688 | 0.69 | ALDH1A1 (0.69) | ALDH1A1KMT2AMAPTSMN1; SMN2NPSR1 | |
| Bicarbonate SCHEMBL7614611 | 0.69 | ALDH1A1 (0.61) | ALDH1A1KMT2AGAAMAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1099420-C | Substituted spiroheterocyclic 1H-3-arylpyrrolidine-2,4-dione derivatives, methods of preparing them and their use as pest-control agents | BAYER AG (DE) | 2003-01-22 | — | — | CN | disclosed |
| CN-1126475-A | Substituted spiroheterocyclic 1H-3-arylpyrrolidine-2,4-dione derivatives, methods of preparing them and their use as pest-control agents | BAYER AG (DE) | 1996-07-10 | — | — | CN | disclosed |