Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410045 | 0.87 | ALOX5AP (0.33) | — | |
| SCHEMBL27411547 | 0.71 | P2RX1 (0.38) | MEN1HTTKMT2A | |
| SCHEMBL5754313 | 0.68 | MEN1 (0.37) | RPS6KB1MEN1HTTKMT2A | |
| SCHEMBL7943945 | 0.66 | KMT2A (0.39) | RPS6KB1MEN1HTTKMT2A | |
| SCHEMBL8102083 | 0.58 | GAA (0.44) | — | |
| SCHEMBL5843666 | 0.55 | CYP3A4 (0.71) | MEN1HTTKMT2A | |
| SCHEMBL9630036 | 0.54 | AHR (0.70) | MEN1KMT2A | |
| SCHEMBL27914994 | 0.52 | NISCH (0.34) | KMT2A | |
| SCHEMBL28766936 | 0.51 | TYR (0.49) | MEN1HTTKMT2A | |
| SCHEMBL7906570 | 0.51 | AHR (0.70) | MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1226803-A | Diphenyl heterocycles as potassium channel modulators | BRISTOL MYERS SQUIBB CO (US) | 1999-08-25 | — | — | CN | claimed |
| CN-1116287-C | Diphenyl heterocycles as potassium channel modulators | BRISTOL MYERS SQUIBB CO (US) | 2003-07-30 | — | — | CN | disclosed |
| CN-1226803-A | Diphenyl heterocycles as potassium channel modulators | BRISTOL MYERS SQUIBB CO (US) | 1999-08-25 | — | — | CN | disclosed |